The formation of new blood vessels, angiogenesis is an important and strictly controlled process that under normal circumstances takes place during embryonic development in wound healing and in the female menstruation cycle. However, in several diseases for instance cancer there is an exaggerated angiogenesis that leads to a disorganized and dysfunctional vasculature that may propagate the disease. Vascular Biology deal with the research studies on how angiogenesis is regulated both during embryo development in adults and in diseases mainly cancer. We also study the mechanisms underlying the formation of functional lymphatic vessels and the development of fibrosis. The vascular network consists of both small and large vessels specifically designed to accommodate varying levels of blood flow and pressure, depends upon the location within the body or large conduit vessels versus small microvessels within the capillary beds in tissues.